AMR

Antimicrobial resistance

Once likened to a slow-moving tsunami,
now advancing swiftly and fiercely,
demanding urgent action.

References

Antimicrobial Resistance Collaborators. (2022). Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. The Lancet; 399(10325): P629-655.

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Drug-Resistant Infections: A Threat to Our Economic future (March 2027)

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What is AMR?
Antimicrobial resistance (AMR) is when micro-organisms bacteria, fungi, viruses and parasites—resist drugs that used to be effective at treating them.

AMR Causes Today

Each year, an estimated 7.7 million deaths are associated with bacterial infections

Antimicrobial Resistance Collaborators Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399:629–655.

Rising AMR rates have been documented over the past two decades. Projections from high-income countries predict that resistance to third-line antibiotics and last-resort drugs could be 2.1 times higher in 2035 compared to rates seen in 2005.

In EU/EEA 33,000

Deaths per year which is equal to deaths from influenza, HIV/AIDS,
and tuberculosis combined

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In India
56,000

Newborn deaths per year 

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In the U.S., more than

2.8 million +

antibiotic resistant infections occur each year.

35,000+

deaths from Antibiotic Resistant each year

Why do bacteria become antibiotic resistant?

Over use and misuse of medications by patients
Antibiotics neutralized and rendered ineffective
Change on cellular structure prevent antibiotics from attaching to cell wall
Genetic material mutation, so antibiotics can’t recognize bacteria
Antibiotic expelled out before damage can be done (efflux pumps)
Defined:
what are the different
types of resistance?

Antibiotic resistance

When bacteria changes in a way that makes antibiotics ineffective.

Antimicrobial resistance

When microbes, such as bacteria, fungi or viruses, change in a way that makes the drugs used to treat them ineffective.

Drug-resistant infections

The illnesses that are caused by resistant microbes, resulting in an infection that is much harder – or potentially impossible – to treat.